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Performing cellular computations with engineered bacteria has enormous importance in biocomputer
technology development at the micron scale, where microprocessor-based computers have limitations due to
energy, cost and technological constraints. Here, we designed and built artificial neural networks with
molecular engineered bacteria that can identify prime numbers, vowels, and even determine the maximum
number of pieces of pizza or pie that can be obtained from a given number of straight cuts. In addition, the
„intelligent‟ bacteria can answer mathematical questions such as whether a number n‟s factorial is divisible by
n × (n + 1)/2 OR whether a number n‟s square can be expressed as the sum of three factorials. All those
problems are classic abstract computational problems and are solved by a computer by writing codes in
Python or C. Introducing such abstract computational capability in living cells, will be a step forward in
biocomputer technology development and may help understanding the biochemical nature of „intelligence‟. |