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Polymeric materials such as polymer brushes, hydrogels and nanofibrous coatings on planer and curved
interfaces that are amenable toward facile multi-functionalization with biological recognition, imaging,
therapeutic and targeting agents are attractive platforms for addressing many challenges faced in
conventional diagnostics and therapy. The talk will report our approaches in fabricating novel polymeric
coatings, nanogels and nanofibers that can modulate recognition of analyte or delivery of therapeutic
agents in a stimuli-responsive manner. In particular, I will highlight the utilization of simple, yet
powerful, organic transformations to tailor polymeric materials for target applications. Examples of
tailoring functional interfaces either through covalent or non-covalent interactions to impart particular
attributes necessary for certain applications from our recent work will be presented. |