| Description: | [DCS Visitor's Seminar] Dr. Soumen K. Samanta (University of Maryland, College Park, USA) -- Supramolecular Self-Assembly: From Molecular Machine to Biomedical Application |
| Date: | Wednesday, Jul 04, 2018 |
| Time: | 4 p.m. - 5:30 p.m. |
| Venue: | TRC Auditorium (2nd Floor) |
| Details: | Nature creates its own species by utilizing self-assembly processes. Most sophisticated biological machineries like ATP Synthase, bacterial flagellar motor are nothing but self-assemblies of multiple components held together by noncovalent interactions. While man-made machineries are advanced enough to exhibit functions, they are still at their infancy to mimic the sophisticated functions like biological machines. Here, I present the state-of-the-art designing of supramolecular nanorotors that undergo rotational motions. Rotational motion of nanorotors can be controlled by adding external additives mimicking speed regulation in bacterial flagellar motor. Self-assembly phenomenon was also utilized to create giant supramolecular architectures that are well-suited to study drug delivery and imaging for theranostic application. Fujita-type metal organic polyhedron (MOP) was functionalized with cucurbit[n]uril (CB[n]). Exceptional recognition properties of CB[n] were combined with large structure and easy functionalization of MOP for targeted and nontargeted drug delivery and imaging applications. |
| Calendar: | Seminar Calendar (entered by sds) |