| Details: |
Radicals play an important role in bond-forming and bond-breaking processes.1
In organic
chemistry, however, carbon-centred radicals are usually observed as rather short-lived
intermediates. In recent years there have been reports on the isolable carbon based
delocalized and localized radicals.
2 One of the synthetic route for the generation of carbon
based radicals could be the 1-e reduction of corresponding carbocation.
In this talk I will discuss the convenient synthetic route for the syntheses of different kinds
of pyrrolinium cations, which we have used for the synthesis of carbon centre based
localized and delocalized radicals.
3
References
(1) See selected recent review: M. Hayyan, M. A. Hashim and I. M. AlNashef, Chem. Rev. 2016, 116,
3029‒3085.
(2) D. Mandal, R. Dolai, N. Chrysochos, P. Kalita, R. Kumar, D. Dhara, A. Maiti, R. S. Narayanan, G.
Rajaraman, C. Schulzke, V. Chandrasekhar and A. Jana, Org. Lett. 2017, 19, 5605–5608.
(3) D. Mandal, S. Sobottka, R. Dolai, A. Maiti, D. Dhara, P. Kalita, R. S. Narayanan, V. Chandrasekhar,
B. Sarkar and A. Jana, Chem. Sci. 2019, Accepted Manuscript, DOI: 10.1039/C8SC05477K. |