| Details: |
Genomic sequences are made from four nucleotides, A, T, C, and G. Several processes such as mutation, transposition, recombination, translocation, and excision, introduce variations in these sequences. Different patterns of nucleotide sequences are known to occur in genomes of different species. Such patterns ("genomic signatures" or “words”) are an emerging area of study in biology. Long range correlations are also known to exist in genomes at different length scales, and genome sequences have been shown to be multi-fractals. In this talk, I will discuss how these genomic patterns can be used for classification of closely related genomes using the methods of Chaos Game Representation and multi fractal analysis.
|